Cardigan Peptide 99%

Cardigan Peptide 99% is a synthetic tetrapeptide material with the sequence Ala-Glu-Asp-Arg, often shortened as AEDR. In the peptide market, it is also commonly connected with the name Cardiogen. On paper, it looks simple. But don't let its size fool you-small peptides like Cardiogen are designed to send big signals at the cellular level.

Its molecular formula is C18H31N7O9, with a molecular weight of about 489.5 g/mol. That puts it in the lightweight class of peptides-fast-acting, easily absorbed, and built to interact with cells in ways larger proteins can't.Cardigan belongs to the category of bioregulator peptides. These are short chains of amino acids that don't just mimic hormones or act as performance boosters-they work by regulating the expression of genes, proteins, and enzymes that control how cells repair, grow, and adapt.

Shaanxi Medibridge Biotech Co., Ltd. supplies this material with HPLC purity testing, batch traceability, and document support. Raw powder, small vial filling, custom mg/vial options, and private label service are available for research-use projects.

Modulating cardiomyocyte metabolism

Cardigan seems to encourage heart muscle cells to use their energy more efficiently, improving mitochondrial integrity and glycogen storage. For the heart, which never gets a break, better energy management means stronger recovery and resilience when under stress.

Suppressing unnecessary cell death (apoptosis)

Under stress, cells often self-destruct through the p53 pathway. Cardigan has been shown in research models to turn down this pathway, allowing healthy cells to survive instead of being prematurely cleared out.

Strengthening the cell's framework

Cardigan boosts the production of cytoskeletal proteins like actin, vimentin, and tubulin, as well as nuclear matrix proteins like lamin A and C. Translation? The scaffolding that gives cells their shape and stability gets stronger, making them more resilient under pressure.

Protecting DNA integrity

Inside the nucleus, Cardigan can help block enzymes that break down DNA. This protective role keeps genetic material stable, reducing cellular "wear and tear" and supporting long-term cell function.

Selective apoptosis in tumor cells

In contrast to its protective role in healthy cells, Cardigan has shown the ability to increase apoptosis in cancerous tissues. This selective "double action" makes it especially intriguing for future therapeutic research.

Disrupts tumor microenvironment

Some evidence points to Cardigan altering blood supply and structure within tumors, making them less stable and more vulnerable to breakdown.

Fibroblast modulation in aging tissues

Cardigan has been studied in aging prostate fibroblasts, where it restored signaling closer to youthful levels. This suggests broader anti-aging and regenerative potential.

Collagen and elastin regulation

By influencing extracellular matrix proteins, Cardigan may help tissues maintain flexibility, strength, and integrity-critical factors in overall performance and recovery.

In cardiac models, even brief dosing schedules reduced mortality, preserved mitochondrial integrity, and minimized scar tissue formation. In oncology models, dosing cycles encouraged tumor apoptosis and necrosis while sparing healthy tissue.

The key takeaway is that Cardigan seems to work best in targeted, intermittent pulses, supporting the body's natural repair systems rather than forcing continuous overstimulation. That's part of what makes it stand out among bioregulator peptides-it's less about "more is better" and more about strategic timing.