BPC-157 powder (Body Protection Compound-157) is a stable gastric-derived 15-pinion (sequence GEPPPGKPADDAGLV). Initially developed as PL-14736/PLD-116, it was first used in research on gastrointestinal mucosal protection and has since been widely explored in areas such as musculoskeletal repair.
As of 2024, 36 studies (35 animal/in vitro and 1 small-scale human retrospective study) have been included, suggesting its ability to improve structural and biomechanical outcomes in muscle, tendon, ligament, and bone injury models.
Shaanxi Medibridge specializes in research-grade peptides, with BPC-157 purity ≥99.85%; each batch is traceable, impurities are strictly controlled, customization and rapid delivery are supported, and stable support is provided for key experiments.

COA
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Product Name |
CAS Number |
Batch Number |
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BPC 157 |
137525-51-0 |
MB2511151528 |
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Manufacturer Date |
Analysis Date |
Expiry Date |
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2025-11-15 |
2025-11-16 |
2027-11-14 |
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Sample Qty Base |
Packing |
Test Method |
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450.52 GS |
10GS/BOTTLE |
HPLC |
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Item |
Standard |
Results |
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Purity |
≥98% |
99.85% |
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Peptide Assay |
≥80% |
83.29% |
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Mass Spectrum |
1419.56 |
1419.56 |
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Solubility |
Soluble in water |
Complies |
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Clarity and color of solution |
Clear and colorless |
Clear and colorless |
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Sodium salt |
<5.0% |
2.52% |
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Water |
≤7.0% |
2.33% |
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Residual Solvent: |
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Methanol |
≤0.3% |
Complies |
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Isopropanol |
≤0.5% |
Complies |
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Acetonitrile |
≤0.041% |
0.005% |
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Methylene Chloride |
≤0.06% |
0.006% |
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N,N-Dimethylformamide |
≤0.075% |
Complies |
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Triethylamine |
≤0.029% |
Complies |
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Tert-butyl methyl ether |
≤0.5% |
0.003% |
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Endotoxin |
≤0.5 EU/mg |
Complies |
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Microbial Limit |
Total aerobic bacteria <100 CFU/g Total yeast & mold <50 CFU/g |
<50 CFU/g <10 CFU/g |
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Storage |
Keep in dark and cool dry place (-20 to 8°C) |
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Conclusion |
The batch conforms to the IN-HOUSE standard |
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Specification
1. Ultra-high purity (≥99.85%), confirmed by HPLC and LC-MS.
2. Complete traceability for each batch.
3. Strict control over relevant peptides and residues.
4. Flexible supply options.
5. Short delivery time, ensuring the integrity of peptides throughout the journey from our warehouse to your laboratory.
6. Professional technical support available upon request.
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Form |
Sample Order |
Specification |
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Raw powder |
1 g |
Purity is NLT 99.85% |
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Vials |
10 vials |
3ml/5ml/7ml/15ml vials etc. |
The Story of BPC Mechanism(For Academic/Research Exchange Only.)
Bpc-157 is like flipping up several main switches of the "repair site" at once: first, it opens up the blood passage to allow oxygen and nutrients to enter; Then draw the fibroblasts to the side of the wound and urge them to spread collagen and build scaffolding. At the same time, put the brakes on excessive inflammation and don't let the scene get more and more chaotic as you try to save it. Finally, raise the "antenna" of the cells for the growth hormone in the body, amplifying their original repair signals.
"Unblocking the blood vessels" (supply first, then repair) : It enables microvessels to dilate and new capillaries to grow. The core lies in the rapid activation of endothelial nitric oxide (eNOS/NO), along with the "angiogenesis" route of VEGF-VEGFR2-AKT. The result is that the damaged area will have water and electricity more quickly, and then there will be materials available for subsequent repairs.
"Pulling workers in" (sending cells to where they should go) : In tissues with low blood supply such as tendons, repair relies on fibroblasts moving, adhering, and spreading collagen. Bpc-157 powder will expand the "starter" for cell adhesion/migration (such as FAK-paxillin), making the cells more resistant to stress, enabling faster external growth and stable paving.

"Amplifying endogenous repair broadcasting" (raising the antenna) : It up-regulates the growth hormone receptor (GHR) of tendon cells, which is equivalent to increasing the sensitivity to GH/IGF. In plain words, it means that "the same body signals are heard more clearly by cells and they work harder", and thus collagen production, cross-linking and remodeling are more in place.
"Inflammation cooling down" (stop losses without causing trouble) : Inflammation is necessary during the acute stage, but it should not be excessive. Bpc-157 will retract the "fire" of COX-2, TNF - α, and IL-6, preventing neutrophils from overcrowding the repair site, making the environment cleaner and the tissue less likely to be slowed down by secondary damage.


How to Continue Validation in Experimental/Clinical Research (Suggested Directions)
1. Randomized, double-blind, placebo-controlled trials applied in the early postoperative period (such as Achilles tendon repair/cruciate ligament reconstruction), with predefined structural + biomechanical + functional outcomes, combined with imaging and biomarkers (VEGFR2/NO/ERK pathway activation spectrum).
2. Local administration gradient dose study (perioperative period/ultrasound-guided peritendinal injection) compared with systemic administration; And carry out human pharmacokinetic/tissue exposure studies to determine the "effective exposure window".
3. Quality/Impurities and immunogenicity assessment, establishing a GMP-grade raw material and placebo-controlled formulation system.
FAQ
Q: What is the material?
A: Synthetic pentadecapeptide BPC 157 powder(GEPPPGKPADDAGLV), lyophilized acetate salt, research Use Only.
Q: How are identity and purity verified?
A: RP‑HPLC purity ≥99.85% (area%) with LC‑MS/HR‑MS confirmation and full chromatograms.
Q: What are endotoxin and bioburden levels?
A: Typical endotoxin ≤0.5 EU/mg.
Q: How do I store it?
A: Keep lyophilized vials at −20°C (dry, dark); store aliquoted solutions at −20°C or 2–8°C short‑term.
Q: What working ranges should I start with?
A: In vitro 10–1000 nM (≈0.014–1.4 μg/mL); any in vivo dosing must follow approved protocols.
Q: What customization are offered?
A: We can provide custom mg/vials and support customization of vials in multiple sizes.
Shaanxi MediBridge provides research peptides for leading global research institutions and universities. Our BPC-157 (GEPPPGKPADDAGLV) is shipped in freeze-dried powder form with a purity of ≥99.85%, verified by HPLC and LC-MS. We strictly control the impurity content and offer customized filling and prompt delivery.
If you are looking for a stead peptide supplier, feel free to contact email: hi@medibridgeapi.com or WhatsApp +44 07548632075. Research use only.
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