Gymnemic acid I is derived from the leaves of Gymnema sylvestre. In practice, the plant material is first extracted to obtain a fraction containing multiple saponin components, after which Gymnemic acid I is separated and purified as an individual compound. Compared with general Gymnema extracts or total gymnemic acids, this process results in a single, well-defined ingredient with a clear chemical profile and more consistent batch characteristics, supplied in powder form for controlled use.
From an application perspective, Gymnemic acid I is best known for its association with sweet taste modulation and sugar-related research. It is commonly discussed as a key component behind the "antisweet" property of Gymnema, and is often referenced in formulation work focused on sugar reduction strategies or sugar-intake–related product concepts. In addition, it is frequently used in formulation evaluation and ingredient comparison when developing nutrition-oriented products, especially in dietary supplement and functional nutrition projects where Gymnema-derived materials are considered. In most cases, its role is to support formulation design, ingredient screening, or reference comparison rather than direct use as a finished consumer ingredient.
Shaanxi Medibridge Biotech Co., Ltd. supplies Gymnemic acid I with controlled specifications suitable for research and formulation development. We focus on stable quality, clear documentation, and flexible supply options to support ingredient evaluation, product development, and long-term cooperation with formulation and R&D teams.
COA
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Product Name |
CAS Number |
Batch Number |
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gyMneMic acid I |
122168-40-5 |
MB2601081500 |
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Manufacturer Date |
Analysis Date |
Expiry Date |
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2026-01-08 |
2026-01-09 |
2028-01-07 |
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Sample Qty Base |
Packing |
Test Method |
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2.38KGS |
10GS/ BOTTLE |
HPLC |
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Item |
Standard |
Results |
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Appearance |
White to pale yellow crystalline powder |
Conforms |
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Identification |
Conforms to Gymnemic acid I |
Conforms |
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Assay (Purity) |
≥ 98.0% |
98.50% |
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Molecular Formula |
C₄₃H₆₆O₁₄ |
Conforms |
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Molecular Weight |
806.98 |
Conforms |
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Loss on Drying |
≤ 5.0% |
2.80% |
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Residue on Ignition |
≤ 2.0% |
0.90% |
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Heavy Metals |
≤ 20 ppm |
< 10 ppm |
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Arsenic (As) |
≤ 2 ppm |
< 0.5 ppm |
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Lead (Pb) |
≤ 2 ppm |
< 0.5 ppm |
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Cadmium (Cd) |
≤ 1 ppm |
< 0.1 ppm |
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Mercury (Hg) |
≤ 0.1 ppm |
< 0.05 ppm |
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Solubility |
Soluble in DMSO |
Conforms |
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Storage |
Store in cool & dry place. keep away from strong light and heat |
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Conclusion |
The batch conforms to the IN-HOUSE standard |
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Typical Application Areas
Formulation Evaluation
Gymnemic acid I is often used during formulation evaluation when Gymnema-derived ingredients need to be examined at a more detailed level. As a purified single compound, it allows R&D teams to work with a clearer and more consistent material when comparing ingredients or testing formulation behavior in early development stages.
Sweetness Control
In nutrition-related projects, Gymnemic acid I is commonly referenced in work related to sweetness modulation and sugar-reduction concepts. It is typically included during formulation trials to help assess how Gymnema-based components interact with different formulation systems, rather than being positioned as a finished-product ingredient.
Reference Material
Gymnemic acid I is also used as a reference material to support internal testing, documentation, and technical discussions. Typical use cases include dietary supplement development, functional nutrition research, and product concept validation, where defined composition and batch consistency are important for comparison and record-keeping.
How It Is Used
Dosage Screening
Gymnemic acid I is commonly used during early-stage dosage screening to help determine suitable inclusion levels when working with Gymnema-related ingredients. Its single-compound nature makes it easier to observe formulation responses across different concentration ranges during development trials.
Blending Trials
In practical formulation work, Gymnemic acid I may be blended with other functional ingredients as part of small-scale trials. These tests are mainly used to check compatibility, handling behavior, and overall stability within multi-ingredient systems before moving forward with more complex formulations.
Comparative Testing
Gymnemic acid I is often applied in comparative testing alongside Gymnema extracts or other related materials. This allows formulators to evaluate differences in behavior, consistency, or formulation performance using a clearly defined reference component.
Physical Properties
Gymnemic acid I is supplied as a white to pale yellow crystalline powder with a relatively uniform appearance. As a purified single compound, it shows more consistent physical characteristics compared with mixed Gymnema extracts, which helps reduce variability during handling and testing.
In terms of solubility, Gymnemic acid I is soluble in DMSO and has limited solubility in aqueous systems. During formulation and laboratory work, it is usually handled using appropriate solvents or dispersed as part of controlled trials rather than being added directly to water-based systems.
Under normal storage conditions, Gymnemic acid I remains stable when kept in a cool, dry environment and protected from moisture and light. Standard laboratory handling practices are generally sufficient, and no special processing equipment is required beyond typical R&D use.
Who Uses It
Gymnemic acid I is mainly used by R&D teams working with Gymnema-derived ingredients who require a material with a clearly defined composition for evaluation and comparison.
It is commonly selected during formulation screening when comparing single compounds with plant extracts or assessing behavior in different formulation systems.
Gymnemic acid I is also used for internal testing, documentation, and long-term development work where consistency and traceable specifications are important.
Gymnemic acid I vs Gymnema Extract
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Item |
Gymnemic acid I |
Gymnema Extract |
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Material Type |
Single, purified compound |
Multi-component plant extract |
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Composition |
One defined triterpenoid saponin |
Mixture of gymnemic acids and other plant constituents |
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Source |
Isolated from Gymnema sylvestre leaves |
Extracted directly from Gymnema sylvestre plant material |
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Processing Level |
Further separated and purified |
Standard extraction and concentration |
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Consistency |
High, with clear chemical identity |
Varies depending on extraction method and specification |
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Typical Use |
Reference material, formulation evaluation, R&D studies |
General ingredient use in formulations |
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Formulation Role |
Used for comparison, screening, and controlled testing |
Used as a functional botanical ingredient |
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Flexibility in R&D |
Suitable for precise dosage and comparison work |
More suitable for broader formulation concepts |
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Application Stage |
Research and development stage |
Development to commercial formulation stage |
Why Choose Us
Shaanxi Medibridge Biotech Co., Ltd. supply Gymnemic acid I as a clearly defined single compound rather than a mixed botanical extract. This allows customers to work with a material of known composition and consistent characteristics, which is especially important for research, formulation evaluation, and comparison work involving Gymnema-derived ingredients.
Our focus is on controlled specifications and batch-to-batch consistency. Each batch is produced and checked under defined quality standards, with supporting documentation available to facilitate internal evaluation, technical review, and project continuity. This approach helps reduce variability and supports repeated use across different development stages.
We works closely with customers in dietary supplement and functional nutrition development, providing flexible supply options to match laboratory testing, formulation screening, and ongoing projects. Our experience with plant-derived ingredients allows us to support long-term cooperation with a practical and reliable supply approach.
FAQ
Q: Is Gymnemic acid I the same as Gymnema extract?
A: No, Gymnemic acid I is a purified single compound, while Gymnema extract contains multiple components from the plant.
Q: What is Gymnemic acid I mainly used for?
A: It is mainly used for research, formulation evaluation, and ingredient comparison related to Gymnema-based materials.
Q: Is Gymnemic acid I water-soluble?
A: It has limited water solubility and is more commonly handled using suitable organic solvents during development work.
Q: What industries commonly work with Gymnemic acid I?
A: It is most often used in dietary supplement development, functional nutrition research, and ingredient evaluation projects.
Q: Can Gymnemic acid I be used directly in finished products?
A: It is typically used at the research and formulation stage rather than as a direct finished-product ingredient.
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