GHRP-2 is a synthetic hexapeptide that acts as a potent agonist of the growth hormone secretagogue receptor (GHSR-1a), the same receptor family engaged by endogenous ghrelin. In pituitary and hypothalamic models, the compound triggers a rapid surge in growth hormone (GH) secretion, often with a characteristic pulse profile that makes it valuable for studying GH physiology, IGF-1 regulation, and downstream anabolic signaling.
Thanks to its strong and reproducible GH-releasing profile, the material is widely used in GH stimulation paradigms, comparative studies versus GHRH analogs (e.g., Sermorelin, Tesamorelin), and models that investigate bone, cartilage, and metabolic repair. The product is strictly labeled for research use only and is not intended for diagnostics, therapy, or self-administration.
COA
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Product Name |
CAS Number |
Batch Number |
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GHRP-2 |
158861-67-7 |
MB2508261715 |
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Manufacturer Date |
Analysis Date |
Expiry Date |
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2025-08-26 |
2025-08-27 |
2027-08-25 |
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Sample Qty Base |
Packing |
Test Method |
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715 GS |
5GS/ BOTTLE |
HPLC |
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Item |
Standard |
Results |
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Purity |
≥98% |
98.57% |
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Peptide Assay |
≥80% |
88.91% |
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Mass Spectrum |
817.97 |
817.97 |
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Solubility |
Soluble in water |
Complies |
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Clarity and color of solution |
Clear and colorless |
Complies |
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salt |
<5.0% |
1.35% |
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Water |
≤7.0% |
2.40% |
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Storage |
Keep in dark and cool dry place (-20 to 8°C) |
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Conclusion |
The batch conforms to the IN-HOUSE standard |
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Specifications (for research use only)
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Form |
Sample Order |
Specification |
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Raw powder |
1 g |
Purity is NLT 99% |
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Vials |
10 vials |
3ml/5ml/7ml/15ml vials etc. |
Literature Snapshot
in circulating GH within minutes of exposure, followed by a predictable return to baseline over 2–3 hours. This short, high-amplitude GH pulse makes it a practical tool for modelling somatotroph responsiveness, IGF-1 regulation, and downstream anabolic markers such as collagen synthesis and protein turnover.
In hypothalamic–pituitary models, the compound selectively activates GHSR-1a, enabling researchers to differentiate PLC/Ca²⁺-linked signaling from cAMP-driven GHRH pathways. Animal studies also report measurable changes in feeding behaviour, glucose handling, and bone-remodelling indices, supporting its use in metabolic and regenerative research. These characteristics explain why laboratories frequently employ the material in GH stimulation tests, combination protocols with GHRH analogs, and studies of endocrine reserve.
Scientific Visualization
Sermorelin vs Tesamorelin vs GHRP
Targets GHRH receptors in the anterior pituitary. Activates the cAMP/PKA signaling pathway. Promotes pulsatile GH secretion. Mimics natural GH rhythms. Used in research,GH deficiency models, and anti-aging studies. Functional core fragment of endogenous GHRH. Emphasizes physiological exposure.
Also binds to GHRH receptors, but with enhanced stability. Activates the same cAMP/PKA pathway. Elevates IGF- 1 levels and improves lipid metabolism. Approved for HIV-related lipodystrophy in some regions. Suitable for clinical applications. Longer half-life and greater receptor affinity than. Sermorelin.Often used in therapeutic and translational research.
Activates the PLC一 Ca²+ signaling pathway. Stimulates GH secretion via a distinct mechanism. Supports bone turnover and cartilage regeneration. Commonly used in metabolic and tissue repair studies .Can be combined with Sermorelin for synergistic effects Independent of the GHRH pathway.
FAQ
Q: What is the use of GHRP-2?
A: GHRP-2 is a growth hormone–releasing peptide that stimulates pituitary GH secretion. Most research examines its effects on appetite regulation, metabolism, and GH axis activity.
Q: Is GHRP-2 the same as Sermorelin?
A: No. Sermorelin is a fragment of GHRH, whereas GHRP-2 is a ghrelin-mimetic acting on different receptors. Both raise GH levels but through distinct mechanisms.
Q: Does GHRP-2 increase height?
A: There is no evidence that GHRP-2 increases adult height because the growth plates are already closed. Data on height effects in children are limited and inconclusive.
Q: Does GHRP increase testosterone?
A: Current studies indicate that GHRPs primarily elevate GH and do not directly stimulate testosterone production. Any hormonal changes tend to be indirect and small.
Q: What's the best peptide to build muscle?
A: There is no single "best peptide" in scientific literature. Compounds like IGF-1 analogs, GHRPs, and GHRH analogs show varying effects, but long-term safety and efficacy remain uncertain.
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