Dipeptide Diaminobutyroyl Benzylamide Diacetate is a synthetic biomimetic peptide developed through advanced solid-phase peptide synthesis (SPPS). It is structurally inspired by Waglerin-1, a peptide originally found in snake venom, and engineered to replicate its functional activity in a safe and controlled cosmetic application. With a low molecular weight and well-defined sequence, it demonstrates good formulation compatibility and skin penetration potential.
This ingredient is primarily designed to target expression-related skin concerns by modulating the interaction between nerve signals and facial muscle activity. It is widely used in anti-aging formulations focusing on dynamic wrinkles, helping to improve the appearance of fine lines caused by repetitive facial movements while supporting a smoother and more refined skin texture.
Shaanxi Medibridge Biotech Co., Ltd. specializes in the development and production of high-quality cosmetic peptides, offering reliable raw materials and customized solutions for global personal care brands.
COA
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Product Name |
CAS Number |
Batch Number |
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Dipetide diaminobutyroyl Benzylamide diacetate |
823202-99-9 |
MB2601271030 |
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Manufacturer Date |
Analysis Date |
Expiry Date |
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2026-01-27 |
2026-01-28 |
2028-01-26 |
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Sample Qty Base |
Packing |
Test Method |
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300KGS |
25kg/drum |
HPLC |
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Item |
Standard |
Results |
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Appearance |
White to off-white powder |
Conforms |
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Identification (HPLC) |
Retention time consistent with reference standard |
Conforms |
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Peptide Structure |
β-Ala-Pro-Dab-NH-Bzl · 2Acetate |
Conforms |
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Molecular Formula |
C19H29N5O3·2(C2H4O2) |
Conforms |
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Molecular Weight |
495.58 Da |
Conforms |
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Purity (HPLC) |
NLT 98.0% |
98.66% |
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Solubility |
Soluble in water / DMSO |
Conforms |
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Water Content (Karl Fischer) |
NMT 5.0% |
2.31% |
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Acetate Content |
NMT 15.0% |
8.42% |
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Heavy Metals |
NMT 10 ppm |
Conforms |
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Related Substances |
NMT 2.0% |
Conforms |
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Storage |
Store in cool & dry place. keep away from strong light and heat |
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Conclusion |
The batch conforms to the IN-HOUSE standard |
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Expression Line Targeting Framework
Dynamic Wrinkle Formation Background
Expression lines are primarily formed by repetitive facial muscle movements such as smiling, frowning, and squinting. Over time, these repeated contractions create visible lines in areas where the skin undergoes continuous folding and tension. These wrinkles are typically categorized as dynamic wrinkles and are most prominent in regions with high facial activity.
Targeted Facial Zones
This peptide is commonly applied in formulations designed for areas prone to expression-related wrinkles. Typical target zones include the forehead, where horizontal lines develop from eyebrow movement; the outer eye area, where crow's feet form due to repeated smiling or squinting; and the nasolabial region, where smile lines become more visible with continuous facial motion. These regions represent key focus areas in cosmetic formulations addressing expression-driven skin changes.
Peptide-Based Targeting Approach
In formulation systems, Dipeptide Diaminobutyroyl Benzylamide Diacetate is used as part of a targeted approach to address expression-related skin concerns. Its application is associated with strategies focusing on reducing the visible impact of repetitive facial movements on the skin surface. Due to its peptide structure and compatibility with aqueous systems, it is frequently incorporated into products intended for localized or full-face anti-aging applications.
Application-Oriented Benefit Perspective
From a formulation perspective, this ingredient is positioned within product systems aiming to improve the appearance of skin smoothness and reduce the visibility of expression lines. It is often included in cosmetic designs that focus on maintaining a more relaxed and refined skin appearance in areas affected by frequent facial movement.
Physicochemical Properties
Dipeptide Diaminobutyroyl Benzylamide Diacetate is a synthetic low-molecular-weight peptide with a defined dipeptide structure modified by benzylamide and acetate groups, with a molecular weight of approximately 495.58 Da. Its molecular formula, C19H29N5O3·2(C2H4O2), reflects a peptide backbone combined with acetate salts, contributing to structural consistency and suitability for standardized cosmetic applications. The peptide is water soluble and can also be dissolved in DMSO, allowing compatibility with a wide range of aqueous formulation systems. It is typically supplied as a white to off-white lyophilized powder, supporting convenient handling, storage, and formulation use. For optimal stability, the product should be stored at -20°C in a sealed, moisture-protected environment, while short-term storage at 2–8°C is acceptable.
Applications
Dipeptide Diaminobutyroyl Benzylamide Diacetate is widely used in cosmetic formulations designed for expression line and anti-aging applications. It is commonly incorporated into serums, eye creams, facial creams, and gel-based systems targeting areas prone to dynamic wrinkles, such as the forehead and eye contour. Due to its water solubility and compatibility with aqueous phases, it can be easily integrated into emulsions and lightweight formulations. This peptide is often used in combination with other functional ingredients, including hyaluronic acid and additional peptides, within formulation systems focused on improving skin smoothness and overall appearance.
Safety & Stability
Dipeptide Diaminobutyroyl Benzylamide Diacetate is a synthetic peptide used in cosmetic formulations with a generally favorable safety profile under appropriate formulation conditions. It is intended for topical application and is typically incorporated at low concentrations, supporting its compatibility in a range of personal care systems. As a peptide material, it should be handled under controlled conditions to maintain stability, avoiding prolonged exposure to high temperatures, light, and repeated freeze–thaw cycles. The lyophilized powder form contributes to product stability during storage and transport. Proper storage in a sealed, moisture-protected environment is recommended to preserve peptide integrity over time.
Packaging & Storage
Dipeptide Diaminobutyroyl Benzylamide Diacetate is typically supplied as a lyophilized powder in sealed, moisture-resistant packaging such as aluminum foil bags or vials, ensuring stability during transportation and storage. Customized packaging options are available based on specific quantity and application requirements. For long-term storage, the product should be kept at -20°C in a dry, light-protected environment, while short-term storage at 2–8°C is acceptable. To maintain peptide integrity, it is recommended to keep the container tightly sealed and avoid repeated freeze–thaw cycles and exposure to humidity.
FAQ
Q: What is Dipeptide Diaminobutyroyl Benzylamide Diacetate?
A: It is a synthetic dipeptide commonly used in cosmetic formulations, developed through solid-phase peptide synthesis and supplied as a high-purity raw material for anti-aging applications.
Q: Is this peptide water soluble?
A: Yes, it is water soluble and can also be dissolved in solvents such as DMSO, making it suitable for a wide range of aqueous formulation systems.
Q: What types of formulations is it used in?
A: It is commonly incorporated into serums, eye creams, emulsions, and gel-based systems designed for expression line and skin-smoothing applications.
Q: What is the recommended storage condition?
A: For long-term stability, it should be stored at -20°C in a sealed, moisture-protected environment. Short-term storage at 2–8°C is acceptable.
Q: Can this peptide be used with other cosmetic ingredients?
A: Yes, it is generally compatible with other peptides and common cosmetic ingredients such as hyaluronic acid in formulation systems.
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