In cosmetic formulation work, this GEKG peptide is mainly used in anti-aging, firming, eye care, and wrinkle-care product lines. It is often selected for formulas that focus on smoother skin texture, better-looking firmness, and multi-peptide skin care concepts. Its water solubility also makes it practical for aqueous systems, serums, creams, and other leave-on cosmetic products.
Shaanxi Medibridge Biotech Co., Ltd. supplies this cosmetic peptide raw material in bulk powder or vial form, with purity testing, batch COA, and custom packing support. We can also provide flexible vial size, mg-per-vial filling, private label service, and repeat-batch supply for cosmetic brands, raw material distributors, and formulation labs.
COA
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Product Name |
CAS Number |
Batch Number |
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Tetrapeptide-21 Powder |
960608-17-7 |
MB2601281030 |
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Manufacturer Date |
Analysis Date |
Expiry Date |
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2026-01-28 |
2026-01-29 |
2028-01-27 |
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Sample Qty Base |
Packing |
Test Method |
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400KGS |
25kg/drum |
HPLC |
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Item |
Standard |
Results |
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Appearance |
White to off-white lyophilized powder |
Conforms |
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Identification (HPLC) |
Retention time consistent with reference standard |
Conforms |
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Peptide Sequence |
Gly-Glu-Lys-Gly (GEKG) |
Conforms |
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Molecular Formula |
C15H27N5O7 |
Conforms |
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Molecular Weight |
389.4 |
Conforms |
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Purity (HPLC) |
NLT 98.0% |
98.69% |
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Solubility |
Soluble in water |
Conforms |
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Water Content (Karl Fischer) |
NMT 5.0% |
2.28% |
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Acetate Content |
NMT 12.0% |
6.22% |
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Heavy Metals |
NMT 10 ppm |
Conforms |
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Related Substances |
NMT 2.0% |
Conforms |
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Storage |
Store in cool & dry place. keep away from strong light and heat |
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Conclusion |
The batch conforms to the IN-HOUSE standard |
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What the GEKG Sequence Means
Tetrapeptide-21 has a four-amino-acid sequence: Gly-Glu-Lys-Gly, usually shortened as GEKG. It is a small structure, but not a blank chain. The two glycine residues keep the peptide light and flexible. Glutamic acid brings an acidic side group, while lysine adds a basic side group. This gives the sequence a simple mixed-charge character, which fits well with cosmetic peptide formulation work.
Its molecular weight is about 389.4, so it belongs to the low-molecular-weight peptide group. For a cosmetic raw material, this makes the specification easier to define by sequence, purity, molecular weight, appearance, and solubility. The short GEKG structure is also practical in multi-peptide systems, where formulators often prefer clean, simple peptide materials instead of large or unclear protein fragments.

A Cosmetic Peptide, Not a General Research Peptide
This peptide is mainly positioned as a cosmetic raw material, not a broad laboratory research peptide. Its value is usually discussed around skin care formulas, especially products made for aging care, skin texture, firmness, and fine-line appearance. That is why the page should stay close to formulation language instead of animal models, disease studies, or clinical-style claims.
For product development, the GEKG peptide is more often seen in serums, creams, eye care products, and multi-peptide blends. It works as one part of a cosmetic active system, together with humectants, emollients, botanical extracts, vitamins, or other peptides. The raw powder form gives brands and labs more room to adjust concentration, solvent system, and final product format during formula design.

Powder Form vs. Finished Peptide Solution
Some cosmetic peptide materials are sold as ready-made liquid blends, often mixed with water, glycerin, butylene glycol, or other carriers. This product is supplied as raw powder, so the focus is different. The powder form gives more flexibility for brands, labs, and ingredient distributors who need their own concentration, solvent system, or finished formula design.
For raw peptide powder, the key information is not only the marketing name. Purity, sequence, molecular weight, solubility, moisture level, and batch documents all matter in real supply work. A clear powder specification also makes it easier to arrange bulk purchase, vial filling, sample preparation, and repeat orders under the same quality standard.
This format is especially suitable when the peptide will be used in custom cosmetic formulas, multi-peptide blends, or private-label projects. It can be packed as bulk powder, small vials, or custom mg-per-vial formats according to the order plan.

How It Fits Into Anti-Aging Formulas
Firming Care
The GEKG peptide is often used in formulas built around a firmer skin look. It fits well in creams, lotions, and leave-on products where the formula already contains moisturizers, emollients, and other skin-conditioning ingredients.
Fine-Line Products
For wrinkle-care formulas, this short peptide can be used as part of a broader anti-aging system. It is usually paired with hydrating agents, barrier-support ingredients, or other cosmetic peptides to help create a smoother skin feel and a more refined surface appearance.
Eye Care
Eye care formulas often need mild, low-use-level active ingredients with good compatibility. This peptide is suitable for eye serums, eye creams, and lightweight gels where brands want a clean peptide story without making the formula feel heavy.
Multi-Peptide Blends
It can also be used in multi-peptide concepts. In this type of formula, each peptide has its own role, while the whole system focuses on skin texture, firmness, and aging-care positioning. The small GEKG structure makes it easy to place alongside other cosmetic peptide raw materials.

Formulation Handling Notes
This peptide is water soluble and can fit into aqueous cosmetic systems such as serums, gels, lotions, and light creams. In most cosmetic development work, the powder form is handled as an active raw material first, then adjusted into the final formula according to the target concentration and product type.
Because it is a short peptide material, high heat and long exposure to moisture are usually avoided during processing and storage. Cooling-stage addition is commonly used in peptide formulas, especially when the base contains emulsifiers, humectants, botanical extracts, or other sensitive active ingredients.
For finished products, the final pH, preservative system, and overall formula compatibility still need to match the full ingredient system. This is also why clear batch data matters for Tetrapeptide-21 powder supply, including HPLC purity, LC-MS identification, appearance, solubility, and moisture control.

Quality Markers for This Short Peptide
For a small GEKG peptide, quality is usually shown through a few clear test points. HPLC purity gives the main purity profile. LC-MS confirms whether the molecular weight matches the target sequence. Appearance, solubility, moisture, and residual solvent data help show whether the batch is suitable for cosmetic raw material use.
Since this peptide has only four amino acids, the specification does not need to be complicated, but it does need to be clean and traceable. A stable batch record, clear COA, and repeatable purity standard are more useful than broad wording on the label.
For bulk powder or vial filling orders, we can provide batch documents such as COA, HPLC report, MSDS, and basic specification sheet. Custom purity, packing size, and mg-per-vial formats can also be arranged according to the order plan.
Storage, Packing & Shipping
This peptide raw material should be kept sealed, dry, and protected from strong light. For long-term holding, low-temperature storage is recommended. After opening, repeated exposure to air and moisture should be reduced, especially when the material will be used for cosmetic formulation testing or repeat batch work.
For international shipping, we can arrange suitable packing based on quantity, season, and destination. Sample orders, bulk powder, and custom vial orders can be shipped with product label, batch number, net weight, storage note, and related documents such as COA or MSDS.
FAQ
Q: What is Tetrapeptide-21 used for in cosmetics?
A: It is mainly used in anti-aging, firming, eye care, and wrinkle-care cosmetic formulas.
Q: Is Tetrapeptide-21 powder water soluble?
A: Yes, it is water soluble and fits well in aqueous cosmetic systems.
Q: Is this powder the same as a finished peptide solution?
A: No, this is raw peptide powder, while many finished solutions are already mixed with water, glycerin, or other carriers.
Q:Can it be used in eye care products?
A: Yes, it is commonly used in eye serums, eye creams, and light gel formulas.
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